Health benefits of Coenzyme Q10

Health benefits of Coenzyme Q10

What is Coenzyme Q10?

Coenzyme Q10 (CoQ-10) is a fat soluble molecule that plays a major role in the electron transport chain, and thus cellular respiration. In other words, it helps your body utilize oxygen and glucose to produce energy. You may also hear it referred to as vitamin Q10, ubiquinone or ubidecarenone.

As a ‘coenzyme’, it’s job is to assist another enzyme in doing it’s job. Enzymes are proteins that speed up chemical reactions in the body. The body uses CoQ-10 to make energy needed for cells to grow and stay health as well as acting as an antioxidant.

In general, the supplementation of CoQ-10 is not as easily recommended as some of the other, more well studied supplements. Many of it’s therapeutic effects are not well understood or not well established in the literature. That said, below is a list of beneficial effects that have at least some evidence based support. Many of these benefits require more research.

CoQ Supplement Options


May have protective and therapeutic effects against parkinsons and alzheimers, against depression and may help reduce the symptoms of headaches and migraines.


Appears to have beneficial effects on heart failure and hypertension. May have beneficial effects to reduce post heart attack complications. There is some evidence it reduces left ventricular thickness in diastolic heart failure. May provide a modest increase in HDL-C, especially when combined with a statin. May help reduce the cardiomyopathy effects of anti-cancer drug class of compounds called anthracyclines (doxorubicin and daunorubicin)

Glucose metabolism

May assist beta cell function in the pancreas and subsequent release of insulin. Has been shown to have a protective effect on HbA1c, but not on circulating glucose and thus is not currently recommended as an effective diabetes medication


May be beneficial to asthma patients when augmenting other medications

Exercise and Skeletal Muscle

No convincing evidence that it benefits cardiovascular exercise performance except where fatigue is a factor. In prolonged exercise, there may be a small benefit where fatigue starts to degrade performance. May provide structural support to skeletal muscle cells via stabilizing the membrane, and thus reducing the release of muscle metabolism byproducts that contribute to fatigue. CoQ-10 not shown to be as helpful to reduce fatigue in acute or intense exercises

Other diseases. May be helpful in treating individuals with

  • Fibromyalgia and chronic fatigue syndrome,
  • Prader-willi syndrome
  • Men with poor sperm count or poor sperm motility
  • Age-related macular degeneration
  • Mitochondrial diseases
  • Muscular dystrophies


There are few serious reported side effects of CoQ10. CoQ10 may lower blood sugar levels and blood pressure. Caution should be taken in individuals already at risk of hypoglycemia or hypotension. There is not enough scientific evidence to support the safe use of CoQ10 during pregnancy or breastfeeding

Dosing of supplement

In adults, up to 1,200 milligrams of CoQ10 have been taken in divided doses by mouth daily. Most supplement forms come in 100 mg oral tablets. There is not enough scientific information to recommend the safe use of CoQ10 in children.

Best Dietary Sources of CoQ-10

The best dietary sources include Meat (beef, pork, chicken, fish (highest natural source)), dairy (Cheese, milk and yogurt), Eggs, nuts and legumes, oral supplements.

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